Adult-onset Still disease

adult-onset Still's disease: adult-onset Still disease (AOSD) is a rare inflammatory multisystem disorder characterized clinically by fever of unknown origin, arthralgia or arthritis, hyperleucocytosis, and typical skin rash.

Endpoint definition

Long name Adult-onset Still disease
Hospital Discharge registry ICD-10: M061
Cause of Death registry ICD-10: M061
First defined in version DF5
Latin name Arthritis rheumatoides seronegativa

Summary Statistics

Key figures

All Female Male
Number of individuals 3403 2408 995
Unadjusted prevalence (%) 1.57 1.96 1.06
Mean age at first event (years) 50.01 48.80 52.93
Case fatality at 5-years (%) 2.44 1.87 3.82

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 3.0 3.0 3.0
Recurrence at 6 months (%) 56.60 57.52 54.37

Survival analyses between endpoints


before Adult-onset Still disease
after Adult-onset Still disease

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Drugs most likely to be purchased after Adult-onset Still disease