Hyperfunction of pituitary gland

hyperpituitarism: Disease of the glandular, anterior portion of the pituitary (pituitary gland, anterior) resulting in hypersecretion of adenohypophyseal hormones such as growth hormone; prolactin; thyrotropin; luteinizing hormone; follicle stimulating hormone ; and adrenocorticotropic hormone. Hyperpituitarism usually is caused by a functional adenoma.

Endpoint definition

Long name Hyperfunction of pituitary gland
Hospital Discharge registry ICD-10: E22
Cause of Death registry ICD-10: E22
Level in the ICD-hierarchy 3
First defined in version DF2
Latin name Hyperfunctio hypophysis

Summary Statistics

Key figures

All Female Male
Number of individuals 762 607 155
Unadjusted prevalence (%) 0.35 0.49 0.16
Mean age at first event (years) 38.96 36.35 49.17
Case fatality at 5-years (%) 0.79 0.66 1.29

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 3.0 3.0 3.0
Recurrence at 6 months (%) 55.38 53.54 62.58

Survival analyses between endpoints


before Hyperfunction of pituitary gland
after Hyperfunction of pituitary gland

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Drugs most likely to be purchased after Hyperfunction of pituitary gland