Acromegaly and pituitary gigantism

hyperpituitarism: Disease of the glandular, anterior portion of the pituitary (pituitary gland, anterior) resulting in hypersecretion of adenohypophyseal hormones such as growth hormone; prolactin; thyrotropin; luteinizing hormone; follicle stimulating hormone ; and adrenocorticotropic hormone. Hyperpituitarism usually is caused by a functional adenoma.

Endpoint definition

Long name Acromegaly and pituitary gigantism
Hospital Discharge registry ICD-10: E220, ICD-8: 2530
Hospital Discharge registry: exclude ICD-8 25301
Cause of Death registry ICD-10: E220, ICD-8: 2530
Cause of Death registry: exclude ICD-8 25301
Level in the ICD-hierarchy 4
First defined in version DF2
Latin name Acromegalia

Summary Statistics

Key figures

All Female Male
Number of individuals 114 70 44
Unadjusted prevalence (%) 0.05 0.06 0.05
Mean age at first event (years) 45.14 44.05 46.88
Case fatality at 5-years (%) 0.00 0.00 0.00

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 6.0 4.0 8.0
Recurrence at 6 months (%) 69.30 65.71 75.00

Survival analyses between endpoints


before Acromegaly and pituitary gigantism
after Acromegaly and pituitary gigantism

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Drugs most likely to be purchased after Acromegaly and pituitary gigantism