primary myelofibrosis: Myelofibrosis with myeloid metaplasia is a myeloproliferative disease with annual incidence of approximately 1 case per 100,000 individuals and age at diagnosis around 60 (an increased prevalence is noted in Ashkenazi Jews). Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy, hepatomegaly, portal hypertension.
| Name | THROMBOCYTAEMIA |
|---|---|
| Long name | Essential (haemorrhagic) thrombocythaemia |
| Hospital Discharge registry | ICD-10: D473, ICD-9: 2387B, ICD-8: 2872 |
| Cause of Death registry | ICD-10: D473, ICD-9: 2387B, ICD-8: 2872 |
| First defined in version | DF2, additional |
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 397 | 246 | 151 |
| Unadjusted prevalence (%) | 0.18 | 0.20 | 0.16 |
| Mean age at first event (years) | 59.83 | 58.98 | 61.22 |
| Case fatality at 5-years (%) | 4.28 | 2.03 | 7.95 |
| All | Female | Male | |
|---|---|---|---|
| Median nb. of events per indiv. | 6.0 | 5.0 | 9.0 |
| Recurrence at 6 months (%) | 72.29 | 71.14 | 74.17 |
before Essential (haemorrhagic) thrombocythaemia
after Essential (haemorrhagic) thrombocythaemia
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