Polycythaemia vera

chronic myeloproliferative disorder: A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008)

Endpoint definition

Name POLYCYTVERA
Long name Polycythaemia vera
Hospital Discharge registry ICD-10: D45, ICD-8: 208
Cause of Death registry ICD-10: D45, ICD-8: 208
First defined in version DF2, additional

Summary Statistics

Key figures

All Female Male
Number of individuals 394 198 196
Unadjusted prevalence (%) 0.18 0.16 0.21
Mean age at first event (years) 61.66 61.79 61.53
Case fatality at 5-years (%) 5.33 6.06 4.59

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 8.5 8.0 9.0
Recurrence at 6 months (%) 76.90 76.77 77.04

Survival analyses between endpoints

Plot

before Polycythaemia vera
after Polycythaemia vera

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Drugs most likely to be purchased after Polycythaemia vera