Myelofibrosis

primary myelofibrosis: Myelofibrosis with myeloid metaplasia is a myeloproliferative disease with annual incidence of approximately 1 case per 100,000 individuals and age at diagnosis around 60 (an increased prevalence is noted in Ashkenazi Jews). Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy, hepatomegaly, portal hypertension.

Endpoint definition

Name MYELOFIBROSIS
Long name Myelofibrosis
Hospital Discharge registry ICD-10: C945, ICD-9: 2387A, ICD-8: 209
Cause of Death registry ICD-10: C945, ICD-9: 2387A, ICD-8: 209
First defined in version DF2, additional

Summary Statistics

Key figures

All Female Male
Number of individuals 8 - -
Unadjusted prevalence (%) 0.00 - -
Mean age at first event (years) 34.12 - -
Case fatality at 5-years (%) 0.00 - -

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 - -
Recurrence at 6 months (%) 12.50 - -

Survival analyses between endpoints

Plot

before Myelofibrosis
after Myelofibrosis

Loading survival analyses plot…