Systemic lupus erythematosus

systemic lupus erythematosus: An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.

Endpoint definition

Name M13_SLE
Long name Systemic lupus erythematosus
Hospital Discharge registry ICD-10: M32, ICD-8: 7431
Cause of Death registry ICD-10: M32, ICD-8: 7431
Level in the ICD-hierarchy 3
First defined in version DF2
Latin name Lupus erythematosus disseminatus (LED)

Summary Statistics

Key figures

All Female Male
Number of individuals 538 448 90
Unadjusted prevalence (%) 0.25 0.36 0.10
Mean age at first event (years) 45.61 44.85 49.36
Case fatality at 5-years (%) 3.16 3.13 3.33

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 6.0 7.0 4.0
Recurrence at 6 months (%) 67.47 67.86 65.56

Survival analyses between endpoints

Plot

before Systemic lupus erythematosus
after Systemic lupus erythematosus

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Drugs most likely to be purchased after Systemic lupus erythematosus