Rheumatoid arthritis

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

Long name Rheumatoid arthritis
Hospital Discharge registry ICD-10: M05/M06, ICD-9: 7140A/7140B, ICD-8: 712[1-3]
Cause of Death registry ICD-10: M05/M06, ICD-9: 7140A/7140B, ICD-8: 712[1-3]
Level in the ICD-hierarchy 4
First defined in version DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 6236 4363 1873
Unadjusted prevalence (%) 2.87 3.55 1.99
Mean age at first event (years) 51.63 50.52 54.20
Case fatality at 5-years (%) 1.92 1.47 2.99

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 7.0 7.0 6.0
Recurrence at 6 months (%) 74.44 75.27 72.50

Survival analyses between endpoints


before Rheumatoid arthritis
after Rheumatoid arthritis

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Drugs most likely to be purchased after Rheumatoid arthritis