Endpoint definition
↥| Name | M13_OVERLAP |
|---|---|
| Long name | Other overlap syndromes |
| Hospital Discharge registry | ICD-10: M351 |
| Cause of Death registry | ICD-10: M351 |
| Level in the ICD-hierarchy | 4 |
| First defined in version | DF2 |
| Latin name | Alia syndromata mixta |
Other overlap syndromes
mixed connective tissue disease: Mixed connective tissue disease (MCTD) is a rare autoimmune disorder that is characterized by features commonly seen in three different connective tissue disorders: systemic lupus erythematosus , scleroderma , and polymyositis . Some affected people may also have symptoms of rheumatoid arthritis . Although MCTD can affect people of all ages, it appears to be most common in women under age 30. Signs and symptoms vary but may include Raynaud's phenomenon ; arthritis; heart, lung and skin abnormalities; kidney disease; muscle weakness, and dysfunction of the esophagus. The cause of MCTD is currently unknown. There is no cure but certain medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) , corticosteroids and immunosuppresivedrugsmay help manage the symptoms.
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 246 | 190 | 56 |
| Unadjusted prevalence (%) | 0.11 | 0.15 | 0.06 |
| Mean age at first event (years) | 52.34 | 51.19 | 56.24 |
| Case fatality at 5-years (%) | 3.66 | 3.68 | 3.57 |
Longitudinal metrics
| All | Female | Male | |
|---|---|---|---|
| Median nb. of events per indiv. | 3.0 | 3.0 | 2.5 |
| Recurrence at 6 months (%) | 58.13 | 58.95 | 55.36 |
Survival analyses between endpoints
↥Plot
before Other overlap syndromes
after Other overlap syndromes
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Table
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