Erythema multiforme

erythema multiforme: Erythema multiforme (EM) refers to a group ofhypersensitivity disorders characterized by symmetric red, patchy lesions, primarily on the arms and legs. The cause is unknown, but EM frequently occurs in association with herpes simplex virus , suggesting an immunologic process initiated by the virus. In half of the cases, the triggering agents appear to be medications, including anticonvulsants, sulfonamides, nonsteroidal anti-inflammatory drugs, and other antibiotics. In addition, some cases appear to be associated with infectious organisms such as Mycoplasma pneumoniae and many viral agents. Erythema multiforme is the mildest of three skin disorders that are often discussed in relation to each other. It is generally the mildest of the three. More severe is Stevens-Johnson syndrome . The most severe of the three is toxic epidermal necrolysis (TEN).

Endpoint definition

Name L12_ERYTHEMAMULTIF
Long name Erythema multiforme
Hospital Discharge registry ICD-10: L51, ICD-9: 6951A/6951B/6951C, ICD-8: 69510
Cause of Death registry ICD-10: L51, ICD-9: 6951A/6951B/6951C, ICD-8: 69510
Level in the ICD-hierarchy 3
First defined in version DF2
Latin name Erythema multiforme

Summary Statistics

Key figures

All Female Male
Number of individuals 334 212 122
Unadjusted prevalence (%) 0.15 0.17 0.13
Mean age at first event (years) 47.23 46.53 48.44
Case fatality at 5-years (%) 4.49 4.25 4.92

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 17.07 18.40 14.75

Survival analyses between endpoints

Plot

before Erythema multiforme
after Erythema multiforme

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Drugs most likely to be purchased after Erythema multiforme