Actinic keratosis

actinic keratosis: A precancerous lesion of the skin composed of atypical keratinocytes. It is characterized by the presence of thick, scaly patches of skin. Several histologic variants have been described, including atrophic, acantholytic, and hyperkeratotic variants.

Endpoint definition

Long name Actinic keratosis
Hospital Discharge registry ICD-10: L570, ICD-9: 7020A, ICD-8: 70200
Cause of Death registry ICD-10: L570, ICD-9: 7020A, ICD-8: 70200
Level in the ICD-hierarchy 4
First defined in version DF2
Latin name Keratosis actinica

Summary Statistics

Key figures

All Female Male
Number of individuals 4817 2527 2290
Unadjusted prevalence (%) 2.22 2.06 2.43
Mean age at first event (years) 71.06 70.33 71.87
Case fatality at 5-years (%) 4.69 4.04 5.41

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 2.0 2.0 2.0
Recurrence at 6 months (%) 43.33 39.57 47.47

Survival analyses between endpoints


before Actinic keratosis
after Actinic keratosis

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Drugs most likely to be purchased after Actinic keratosis