Diaphragmatic hernia

congenital diaphragmatic hernia: Congenital diaphragmatic hernia (CDH) is a posterolateral defect of the diaphragm that allows passage of abdominal viscera into the thorax, leading to respiratory insufficiency and persistent pulmonary hypertension with high mortality.

Endpoint definition

Long name Diaphragmatic hernia
Hospital Discharge registry ICD-10: K44, ICD-8: 5513
Cause of Death registry ICD-10: K44, ICD-8: 5513
Level in the ICD-hierarchy 3
First defined in version DF2
Latin name Hernia diaphragmatica

Summary Statistics

Key figures

All Female Male
Number of individuals 5741 3429 2312
Unadjusted prevalence (%) 2.65 2.79 2.46
Mean age at first event (years) 59.38 59.34 59.45
Case fatality at 5-years (%) 3.73 2.74 5.19

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 20.12 21.29 18.38

Survival analyses between endpoints


before Diaphragmatic hernia
after Diaphragmatic hernia

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Drugs most likely to be purchased after Diaphragmatic hernia