Cholangitis (primary sclerosing, PSC), with reimbursement 202

sclerosing cholangitis: A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure.

Endpoint definition

Name K11_CHOLANGI_STRICT
Long name Cholangitis (primary sclerosing, PSC), with reimbursement 202
Hospital Discharge registry ICD-10: K830, ICD-8: 5750[4-5]
Cause of Death registry ICD-10: K830, ICD-8: 5750[4-5]
Conditions required K11_REIMB_202
First defined in version DF3
Latin name Cholangitis

Summary Statistics

Key figures

All Female Male
Number of individuals 238 134 104
Unadjusted prevalence (%) 0.11 0.11 0.11
Mean age at first event (years) 42.88 45.68 39.28
Case fatality at 5-years (%) 2.10 2.24 1.92

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 40.36 38.65 42.18

Survival analyses between endpoints

Plot

before Cholangitis (primary sclerosing, PSC), with reimbursement 202
after Cholangitis (primary sclerosing, PSC), with reimbursement 202

Loading survival analyses plot…

Drugs most likely to be purchased after Cholangitis (primary sclerosing, PSC), with reimbursement 202