Barret oesophagus

Barrett's esophagus: Esophageal lesion lined with columnar metaplastic epithelium which is flat or villiform. Barrett epithelium is characterized by two different types of cells: goblet cells and columnar cells. The symptomatology of Barrett esophagus is that of gastro-esophageal reflux. It is the precursor of most esophageal adenocarcinomas. (WHO)

Endpoint definition

Name K11_BARRET
Long name Barret oesophagus
Hospital Discharge registry ICD-10: K227, ICD-9: 5301B
Cause of Death registry ICD-10: K227, ICD-9: 5301B
Level in the ICD-hierarchy 3
First defined in version DF2

Summary Statistics

Key figures

All Female Male
?
Number of individuals
495 180 315
?
Unadjusted prevalence (%)
0.23 0.15 0.33
?
Mean age at first event (years)
64.03 64.40 63.82
?
Case fatality at 5-years (%)
3.84 1.67 5.08

Longitudinal metrics

All Female Male
?
Median nb. of events per indiv.
1.0 1.0 1.0
?
Recurrence at 6 months (%)
20.40 17.22 22.22

Survival analyses between endpoints

Plot

before Barret oesophagus
after Barret oesophagus

Loading survival analyses plot…

Drugs most likely to be purchased after Barret oesophagus