Cerebral amyloid angiopathy

cerebral amyloid angiopathy: Hereditary cerebral hemorrhage with amyloidosis (HCHWA) describes a group of rare familial central nervous system disorders characterized by amyloid deposition in the cerebral blood vessels leading to hemorrhagic and non-hemorrhagic strokes, focal neurological deficits, and progressive cognitive decline eventually leading to dementia.

Endpoint definition

Name I9_CEREBAMY
Long name Cerebral amyloid angiopathy
Hospital Discharge registry ICD-10: I680
Cause of Death registry ICD-10: I680
Level in the ICD-hierarchy 3
First defined in version DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 24 7 17
Unadjusted prevalence (%) 0.01 0.01 0.02
Mean age at first event (years) 67.37 64.33 68.62
Case fatality at 5-years (%) 8.33 14.29 5.88

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 20.83 - 29.41

Survival analyses between endpoints

Plot

before Cerebral amyloid angiopathy
after Cerebral amyloid angiopathy

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Drugs most likely to be purchased after Cerebral amyloid angiopathy