Optic neuritis

optic neuritis: Optic neuritis is inflammation of the optic nerve, the nerve that carries the visual signal from the eye to the brain.The conditionmay cause sudden, reduced vision in the affected eye(s). While the cause of optic neuritis is unknown, it has been associated with autoimmune diseases, infections, multiple sclerosis , drug toxicity and deficiency of vitamin B-12. Vision often returns to normal within 2-3 weeks without treatment. In some cases, corticosteroids are given to speed recovery. If known, the underlying cause should be treated.

Endpoint definition

Name H7_OPTNEURITIS
Long name Optic neuritis
Hospital Discharge registry ICD-10: H46, ICD-8: 3670[2-9]
Cause of Death registry ICD-10: H46, ICD-8: 3670[2-9]
Level in the ICD-hierarchy 3
First defined in version DF2
Latin name Neuritis optica

Summary Statistics

Key figures

All Female Male
Number of individuals 582 426 156
Unadjusted prevalence (%) 0.27 0.35 0.17
Mean age at first event (years) 39.48 38.53 42.06
Case fatality at 5-years (%) 1.03 1.17 0.64

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 2.0 1.0
Recurrence at 6 months (%) 39.69 41.31 35.26

Survival analyses between endpoints

Plot

before Optic neuritis
after Optic neuritis

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