Guillain-Barre syndrome

Guillain-Barre syndrome: Guillain-BarrC) syndrome (GBS) is the term used to describe a spectrum of rare post-infectious neuropathies that usually occur in otherwise healthy patients. GBS is clinically heterogeneous and encompasses acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy (AMAN) and acute motor-sensory axonal neuropathy (AMSAN), Miller-Fisher syndrome (MFS; see these terms) and some other regional variants.

Endpoint definition

Name G6_GUILBAR
Long name Guillain-Barre syndrome
Hospital Discharge registry ICD-10: G610, ICD-8: 35401
Cause of Death registry ICD-10: G610, ICD-8: 35401
Level in the ICD-hierarchy 3
First defined in version DF2
Latin name Syndroma Guillain-Barré

Summary Statistics

Key figures

All Female Male
Number of individuals 213 101 112
Unadjusted prevalence (%) 0.10 0.08 0.12
Mean age at first event (years) 46.81 44.92 48.50
Case fatality at 5-years (%) 4.23 1.98 6.25

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 2.0 1.0 2.0
Recurrence at 6 months (%) 44.60 39.60 49.11

Survival analyses between endpoints

Plot

before Guillain-Barre syndrome
after Guillain-Barre syndrome

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Drugs most likely to be purchased after Guillain-Barre syndrome