Endpoint definition
↥| Name | ESOSINOPHIL_DISEASE |
|---|---|
| Long name | Eosinophilic disease (BM) |
| Hospital Discharge registry | ICD-10: D721 |
| Cause of Death registry | ICD-10: D721 |
| First defined in version | DF2 |
| Latin name | Eosinophilia |
Eosinophilic disease (BM)
Hypereosinophilic syndrome: The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out.
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 182 | 95 | 87 |
| Unadjusted prevalence (%) | 0.08 | 0.08 | 0.09 |
| Mean age at first event (years) | 53.38 | 51.70 | 55.22 |
| Case fatality at 5-years (%) | 2.20 | 2.11 | 2.30 |
Longitudinal metrics
| All | Female | Male | |
|---|---|---|---|
| Median nb. of events per indiv. | 1.0 | 1.0 | 1.0 |
| Recurrence at 6 months (%) | 41.21 | 43.16 | 39.08 |
Survival analyses between endpoints
↥Plot
before Eosinophilic disease (BM)
after Eosinophilic disease (BM)
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Table
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