lactose intolerance: Inability to fully digest and absorb lactose due to limited or no lactase activity in the small intestine. Congenital intolerance is inherited following an autosomal recessive pattern but is rare. It is more often due to a gradual decline of lactase production in adulthood following the ingestion of fewer lactose-containing foods or secondary to an intestinal mucosal brush-border injury. Prevalence is highest among Asians, Native Americans and Africans. Clinical signs include abdominal cramping, bloating, flatulence and diarrhea following the dietary intake of lactose.
| Name | E4_LACTOSEC |
|---|---|
| Long name | Secondary lactase deficiency |
| Hospital Discharge registry | ICD-10: E731 |
| Cause of Death registry | ICD-10: E731 |
| Level in the ICD-hierarchy | 4 |
| First defined in version | DF2 |
| Latin name | Deficientia lactasae secundaria |
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 14 | 8 | 6 |
| Unadjusted prevalence (%) | 0.01 | 0.01 | 0.01 |
| Mean age at first event (years) | 41.58 | 36.79 | 47.97 |
| Case fatality at 5-years (%) | 0.00 | 0.00 | 0.00 |
| All | Female | Male | |
|---|---|---|---|
| Median nb. of events per indiv. | 1.0 | 1.0 | 1.0 |
| Recurrence at 6 months (%) | 14.29 | 12.50 | 16.67 |
before Secondary lactase deficiency
after Secondary lactase deficiency
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