Disorders of iron metabolism

hereditary hemochromatosis type 1: Hemochromatosis type 1 (classic) is the most common form of hereditary hemochromatosis (HH), a group of diseases characterized by excessive tissue iron deposition. Due to its incidence (1/200-1/1000), it is not considered as a rare disease, unlike the other subforms of the disease

Endpoint definition

Long name Disorders of iron metabolism
Hospital Discharge registry ICD-10: E831
Cause of Death registry ICD-10: E831
Level in the ICD-hierarchy 4
First defined in version DF2
Latin name Perturbationes metabolismi ferri

Summary Statistics

Key figures

All Female Male
Number of individuals 146 60 86
Unadjusted prevalence (%) 0.07 0.05 0.09
Mean age at first event (years) 55.16 55.94 54.62
Case fatality at 5-years (%) 4.11 1.67 5.81

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 4.0 3.0 4.0
Recurrence at 6 months (%) 65.75 58.33 70.93

Survival analyses between endpoints


before Disorders of iron metabolism
after Disorders of iron metabolism

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Drugs most likely to be purchased after Disorders of iron metabolism