hypopituitarism: A condition of diminution or cessation of secretion of one or more hormones from the anterior pituitary gland. This may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions.

Endpoint definition

Long name Hypopituitarism
Hospital Discharge registry ICD-10: E230, ICD-8: 2531
Cause of Death registry ICD-10: E230, ICD-8: 2531
KELA reimboursements codes 101
Level in the ICD-hierarchy 4
First defined in version DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 910 343 567
Unadjusted prevalence (%) 0.42 0.28 0.60
Mean age at first event (years) 42.96 40.88 44.22
Case fatality at 5-years (%) 2.75 1.46 3.53

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 3.0 3.0 3.0
Recurrence at 6 months (%) 59.89 55.98 62.26

Survival analyses between endpoints


before Hypopituitarism
after Hypopituitarism

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