Secondary systemic amyloidosis

amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.

Endpoint definition

Long name Secondary systemic amyloidosis
Hospital Discharge registry ICD-10: E853
Cause of Death registry ICD-10: E853
Level in the ICD-hierarchy 4
First defined in version DF2
Latin name Amyloidosis systemica secundaria

Summary Statistics

Key figures

All Female Male
Number of individuals 46 31 15
Unadjusted prevalence (%) 0.02 0.03 0.02
Mean age at first event (years) 60.39 59.41 62.41
Case fatality at 5-years (%) 34.78 38.71 26.67

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 3.0 3.0 3.0
Recurrence at 6 months (%) 52.17 48.39 60.00

Survival analyses between endpoints


before Secondary systemic amyloidosis
after Secondary systemic amyloidosis

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Drugs most likely to be purchased after Secondary systemic amyloidosis