Eosinophilia

Hypereosinophilic syndrome: The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out.

Endpoint definition

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Name D3_EOSINOPHILIA
Long name Eosinophilia
Hospital Discharge registry ICD-10: D721
Cause of Death registry ICD-10: D721
Level in the ICD-hierarchy 4
First defined in version DF2
Latin name Eosinophilia

Summary Statistics

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Key figures

All Female Male
Number of individuals 182 95 87
Unadjusted prevalence (%) 0.08 0.08 0.09
Mean age at first event (years) 53.38 51.70 55.22
Case fatality at 5-years (%) 2.20 2.11 2.30

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 41.21 43.16 39.08

Survival analyses between endpoints

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Plot

before Eosinophilia
after Eosinophilia

Loading survival analyses plot…