Other or unspecified common variable immunodeficiency

obsolete_common variable immunodeficiency: ['A hypogammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells. Patients with common variable immunodeficiency have marked reduction in serum levels of both immunoglobulin G (IgG) and immunoglobulin A (IgA); about half of these patients also have reduced immunoglobulin M (IgM).', 'A primary immunodeficiency characterized by low levels or absence of all the immunoglobulin classes and lack of B-lymphocytes or plasma cells. It results in recurrent bacterial infections. Complications include autoimmune phenomena and cancer development.', 'Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.']

Endpoint definition

Name D3_CVIDNAS
Long name Other or unspecified common variable immunodeficiency
Hospital Discharge registry ICD-10: D839/D838
Cause of Death registry ICD-10: D838/D839
Level in the ICD-hierarchy 4
First defined in version DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 46 33 13
Unadjusted prevalence (%) 0.02 0.03 0.01
Mean age at first event (years) 47.38 47.48 47.11
Case fatality at 5-years (%) 4.35 6.06 0.00

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 2.5 4.0 2.0
Recurrence at 6 months (%) 56.52 60.61 46.15

Survival analyses between endpoints

Plot

before Other or unspecified common variable immunodeficiency
after Other or unspecified common variable immunodeficiency

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Drugs most likely to be purchased after Other or unspecified common variable immunodeficiency