cryoglobulinemia: Cryoglobulinemia is a type of vasculitis that is caused by abnormal proteins (antibodies) in the blood called 'cryoglobulins.' At cold temperatures, these proteins become solid or gel-like, which can block blood vessels and cause a variety of health problems. Many people affected by this condition will not experience any unusual signs or symptoms. When present, symptoms vary but may include breathing problems; fatigue; glomerulonephritis ; joint or muscle pain; purpura ; Raynaud's phenomenon ; skin death; and/or skin ulcers. In some cases, the exact underlying cause is unknown; however, cryoglobulinemia can be associated with a variety of conditions including certain types of infection; chronic inflammatory diseases (such as autoimmune disease ); and/or cancers of the blood or immune system . Treatment varies based on the severity of the condition, the symptoms present in each person and the underlying cause.
| Name | D3_CRYOGLOBU |
|---|---|
| Long name | Cryoglobulinemia |
| Hospital Discharge registry | ICD-10: D891, ICD-9: 2732A, ICD-8: 2754 |
| Cause of Death registry | ICD-10: D891, ICD-9: 2732A, ICD-8: 2754 |
| Level in the ICD-hierarchy | 4 |
| First defined in version | DF2 |
| Latin name | Cryoglobulinaemia |
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 15 | 6 | 9 |
| Unadjusted prevalence (%) | 0.01 | 0.00 | 0.01 |
| Mean age at first event (years) | 48.30 | 47.50 | 48.83 |
| Case fatality at 5-years (%) | 13.33 | 16.67 | 11.11 |
| All | Female | Male | |
|---|---|---|---|
| Median nb. of events per indiv. | 1.0 | 1.0 | 2.0 |
| Recurrence at 6 months (%) | 33.33 | - | 55.56 |
before Cryoglobulinemia
after Cryoglobulinemia
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