Multiple myeloma and malignant plasma cell neoplasms

multiple myeloma: A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

Endpoint definition

Name CD2_MULTIPLE_MYELOMA_PLASMA_CELL
Long name Multiple myeloma and malignant plasma cell neoplasms
Hospital Discharge registry ICD-10: C90, ICD-9: 203, ICD-8: 203
Cause of Death registry ICD-10: C90, ICD-9: 203, ICD-8: 203
Level in the ICD-hierarchy 3
First defined in version DF4
Latin name Myeloma multiplex et neoplasmata maligna plasmacytorum

Summary Statistics

Key figures

All Female Male
Number of individuals 598 270 328
Unadjusted prevalence (%) 0.28 0.22 0.35
Mean age at first event (years) 65.24 64.36 65.96
Case fatality at 5-years (%) 22.41 19.26 25.00

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 4.0 5.0 4.0
Recurrence at 6 months (%) 65.38 65.19 65.55

Survival analyses between endpoints

Plot

before Multiple myeloma and malignant plasma cell neoplasms
after Multiple myeloma and malignant plasma cell neoplasms

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Drugs most likely to be purchased after Multiple myeloma and malignant plasma cell neoplasms