Melanoma in situ

melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.

Summary Statistics

Key figures

All Female Male
Number of individuals 393 205 188
Unadjusted prevalence (%) 0.18 0.17 0.20
Mean age at first event (years) 65.78 63.21 68.59
Case fatality at 5-years (%) 2.29 0.00 4.79

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 31.30 33.66 28.72

Survival analyses between endpoints


before Melanoma in situ
after Melanoma in situ

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Drugs most likely to be purchased after Melanoma in situ