neoplasm of mature B-cells: A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).
| Name | CD2_FOLLICULAR_LYMPHOMA |
|---|---|
| Long name | Follicular lymphoma |
| Hospital Discharge registry | ICD-10: C82, ICD-9: 2000A |
| Cause of Death registry | ICD-10: C82, ICD-9: 2000A |
| Level in the ICD-hierarchy | 3 |
| First defined in version | DF4 |
| Latin name | Lymphoma non-Hodgkin nodulare (folliculare) |
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 522 | 262 | 260 |
| Unadjusted prevalence (%) | 0.24 | 0.21 | 0.28 |
| Mean age at first event (years) | 61.89 | 61.49 | 62.30 |
| Case fatality at 5-years (%) | 7.28 | 6.11 | 8.46 |
| All | Female | Male | |
|---|---|---|---|
| Median nb. of events per indiv. | 7.0 | 7.0 | 7.0 |
| Recurrence at 6 months (%) | 75.86 | 74.81 | 76.92 |
before Follicular lymphoma
after Follicular lymphoma
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