Diffuse large B-cell lymphoma

diffuse large B-cell lymphoma: Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL; see this term) in adults characterized by a median age of presentation in the sixth decade of life (but also rarely occurring in adolescents and children) with the initial presentation being single or multiple rapidly growing masses (that may or may not be painful) in nodal or extranodal sites (such as thyroid, skin, breast, gastrointestinal tract, testes, bone, or brain) and that can be accompanied by symptoms of fever, night sweats and weight loss. DLBCL has an aggressive disease course, with the elderly having a poorer prognosis than younger patients, and with relapses being common.

Endpoint definition

Name C3_DLBCL
Long name Diffuse large B-cell lymphoma
Cause of Death registry ICD-10: C84/C85/C83, ICD-9: 200, ICD-8: 200
Cancer reg: TOPOGRAPHY codes C42|C77
Cancer reg: MORPHOLOGY codes 9680
Conditions required HLP_C3_DLBCL
Level in the ICD-hierarchy C
First defined in version DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 209 101 108
Unadjusted prevalence (%) 0.10 0.08 0.11
Mean age at first event (years) 64.81 63.80 65.75
Case fatality at 5-years (%) 11.96 4.95 18.52

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 1.42 1.27 1.54

Survival analyses between endpoints

Plot

before Diffuse large B-cell lymphoma
after Diffuse large B-cell lymphoma

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Drugs most likely to be purchased after Diffuse large B-cell lymphoma