Chronic myeloid leukaemia

obsolete_chronic myeloid leukemia: ['Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.']

Endpoint definition

Name C3_CML
Long name Chronic myeloid leukaemia
Cause of Death registry ICD-10: C92, ICD-9: 204, ICD-8: 204
Cancer reg: TOPOGRAPHY codes C42|C77
Cancer reg: MORPHOLOGY codes 9863
Conditions required HLP_C3_CML
Level in the ICD-hierarchy C
First defined in version DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 58 26 32
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 56.74 54.46 58.59
Case fatality at 5-years (%) 12.07 11.54 12.50

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 1.59 - 2.67

Survival analyses between endpoints

Plot

before Chronic myeloid leukaemia
after Chronic myeloid leukaemia

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Drugs most likely to be purchased after Chronic myeloid leukaemia