Alcoholic liver disease

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

Name ALCOLIVER
Long name Alcoholic liver disease
Hospital Discharge registry ICD-10: K70, ICD-8: 5710
Cause of Death registry ICD-10: K70, ICD-8: 5710
Level in the ICD-hierarchy 2
First defined in version DF2
Latin name Morbus hepatis alcoholicus

Summary Statistics

Key figures

All Female Male
Number of individuals 1416 360 1056
Unadjusted prevalence (%) 0.65 0.29 1.12
Mean age at first event (years) 55.54 54.17 56.01
Case fatality at 5-years (%) 30.93 23.89 33.33

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 36.94 40.56 35.70

Survival analyses between endpoints

Plot

before Alcoholic liver disease
after Alcoholic liver disease

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Drugs most likely to be purchased after Alcoholic liver disease