Viral infections of the central nervous system

DOID EFO MESH SNOMED PheWeb

viral meningitis: Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)

Endpoint definition

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Name	AB1_VIRAL_CNS
Long name	Viral infections of the central nervous system
Hospital Discharge registry	ICD-10: A87/A86/A88/A83/A80/A81/A84/A82/A89/A85, ICD-9: 045/046/047/048/049/062/063/064/071, ICD-8: 04[0-3]\|06[2-5]\|071
Cause of Death registry	ICD-10: A86/A88/A85/A87/A80/A89/A81/A82/A84/A83, ICD-9: 045/046/047/048/049/062/063/064/071, ICD-8: 04[0-3]\|06[2-5]\|071
Include	AB1_POLIOMYELITIS, AB1_ATYPICAL_CNS_VIRUS, AB1_RABIES, AB1_MOSQUITO_VIRAL_CNS, AB1_TICK_BORNE_ENCEPHALITIS, AB1_VIRAL_ENCEPHALITIS_NOS, AB1_VIRAL_MENINGITIS, AB1_VIRAN_CNS_INFECTIONS_NOS
Level in the ICD-hierarchy	2
First defined in version	DF2

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1155	697	458
Unadjusted prevalence (%)	0.53	0.57	0.49
Mean age at first event (years)	37.42	36.88	38.24
Case fatality at 5-years (%)	3.90	2.30	6.33

Longitudinal metrics

	All	Female	Male
Median nb. of events per indiv.	1.0	1.0	1.0
Recurrence at 6 months (%)	11.00	11.33	10.48

Survival analyses between endpoints

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Plot

before Viral infections of the central nervous system
after Viral infections of the central nervous system

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Table

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Drugs most likely to be purchased after Viral infections of the central nervous system

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