Secondary parkinsonism

secondary Parkinson disease: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)

Endpoint definition

Name PD2ND
Long name Secondary parkinsonism
Hospital Discharge registry ICD-10: G21
Cause of Death registry ICD-10: G21
First defined in version DF2
Latin name Parkinsonismus secundarius

Summary Statistics

Key figures

All Female Male
Number of individuals 417 190 227
Unadjusted prevalence (%) 0.19 0.15 0.24
Mean age at first event (years) 59.56 59.55 59.56
Case fatality at 5-years (%) 11.99 8.42 14.98

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 30.94 28.95 32.60

Survival analyses between endpoints

Plot

before Secondary parkinsonism
after Secondary parkinsonism

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Drugs most likely to be purchased after Secondary parkinsonism