Gastro-oesophageal reflux disease

gastroesophageal reflux disease: A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa.

Endpoint definition

Name K11_REFLUX
Long name Gastro-oesophageal reflux disease
Hospital Discharge registry ICD-10: K21, ICD-9: 5301A
Cause of Death registry ICD-10: K21, ICD-9: 5301A
Level in the ICD-hierarchy 3
First defined in version DF2
Latin name Morbus refluxualis gastro-oesophageus

Summary Statistics

Key figures

All Female Male
Number of individuals 13141 7566 5575
Unadjusted prevalence (%) 6.06 6.16 5.92
Mean age at first event (years) 54.13 53.73 54.66
Case fatality at 5-years (%) 2.34 1.41 3.59

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 23.93 23.68 24.25

Survival analyses between endpoints

Plot

before Gastro-oesophageal reflux disease
after Gastro-oesophageal reflux disease

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Drugs most likely to be purchased after Gastro-oesophageal reflux disease