Cholangitis (primary sclerosing, PSC)

sclerosing cholangitis: A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure.

Endpoint definition

Name K11_CHOLANGI
Long name Cholangitis (primary sclerosing, PSC)
Hospital Discharge registry ICD-10: K830, ICD-8: 5750[4-5]
Cause of Death registry ICD-10: K830, ICD-8: 5750[4-5]
Level in the ICD-hierarchy 3
First defined in version DF2
Latin name Cholangitis

Summary Statistics

Key figures

All Female Male
Number of individuals 778 401 377
Unadjusted prevalence (%) 0.36 0.33 0.40
Mean age at first event (years) 56.06 54.61 57.61
Case fatality at 5-years (%) 9.77 7.73 11.94

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 40.36 38.65 42.18

Survival analyses between endpoints

Plot

before Cholangitis (primary sclerosing, PSC)
after Cholangitis (primary sclerosing, PSC)

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Drugs most likely to be purchased after Cholangitis (primary sclerosing, PSC)