Barret oesophagus

Barrett's esophagus: Esophageal lesion lined with columnar metaplastic epithelium which is flat or villiform. Barrett epithelium is characterized by two different types of cells: goblet cells and columnar cells. The symptomatology of Barrett esophagus is that of gastro-esophageal reflux. It is the precursor of most esophageal adenocarcinomas. (WHO)

Endpoint definition

Name K11_BARRET
Long name Barret oesophagus
Hospital Discharge registry ICD-10: K227, ICD-9: 5301B
Cause of Death registry ICD-10: K227, ICD-9: 5301B
Level in the ICD-hierarchy 3
First defined in version DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 495 180 315
Unadjusted prevalence (%) 0.23 0.15 0.33
Mean age at first event (years) 64.03 64.40 63.82
Case fatality at 5-years (%) 3.84 1.67 5.08

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 20.40 17.22 22.22

Survival analyses between endpoints

Plot

before Barret oesophagus
after Barret oesophagus

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Drugs most likely to be purchased after Barret oesophagus