Secondary parkinsonism+Parkinsonism in other disease

postencephalitic Parkinson disease: Parkinsonism following encephalitis, historically seen as a sequella of encephalitis lethargica (Von Economo Encephalitis). The early age of onset, the rapid progression of symptoms followed by stabilization, and the presence of a variety of other neurological disorders (e.g., sociopathic behavior; TICS; MUSCLE SPASMS; oculogyric crises; hyperphagia; and bizarre movements) distinguish this condition from primary PARKINSON DISEASE. Pathologic features include neuronal loss and gliosis concentrated in the MESENCEPHALON; SUBTHALAMUS; and HYPOTHALAMUS. (From Adams et al., Principles of Neurology, 6th ed, p754)

Endpoint definition

Name G6_PARKSCND
Long name Secondary parkinsonism+Parkinsonism in other disease
Hospital Discharge registry ICD-10: G21, ICD-8: 3420[8-9]
Cause of Death registry ICD-10: G21, ICD-8: 3420[8-9]
Level in the ICD-hierarchy 3
First defined in version DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 431 198 233
Unadjusted prevalence (%) 0.20 0.16 0.25
Mean age at first event (years) 58.92 58.66 59.13
Case fatality at 5-years (%) 11.60 8.08 14.59

Longitudinal metrics

All Female Male
Median nb. of events per indiv. 1.0 1.0 1.0
Recurrence at 6 months (%) 30.39 28.79 31.76

Survival analyses between endpoints

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before Secondary parkinsonism+Parkinsonism in other disease
after Secondary parkinsonism+Parkinsonism in other disease

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Drugs most likely to be purchased after Secondary parkinsonism+Parkinsonism in other disease